Abstract
COMPARATIVE investigations of the clearance of injected bacteriophage from the circulation of several species of animal have been carried out. Clearance from the chicken, frog and from certain elasmobranch, holostean and teleost fish was very rapid and was associated with the development of neutralizing antibody1,2. In the cyclostomes Petromyzon marinus and Eptatretus stoutii clearance was relatively slow, and little or no neutralizing ability developed in the serum of injected animals2. The insect Samia cecropia cleared 90 per cent or more of the injected dose of bacteriophage from the Hæmolymph between the second and the tenth hour, but no neutralizing activity appeared to develop3. Accelerated secondary clearance has been demonstrated in the chicken, the frog and in some fish, but was not tested in the insect. The following preliminary experiments were carried out to investigate primary and secondary clearance of bacteriophage in other invertebrates as part of an investigation in comparative immunology.
Similar content being viewed by others
Article PDF
References
Uhr, J. W., Finkelstein, S., and Franklin, E. C., Proc. Soc. Exp. Biol. Med., 111, 13 (1962).
Papermaster, B. W., Condie, R. M., Finstad, J., and Good, R. A., J. Exp. Med., 119, 105 (1964).
Bernheimer, A. W., Caspari, E., and Kaiser, A. D., J. Exp. Biol., 119, 23 (1952).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
TAYLOR, A., TAYLOR, G. & COLLARD, P. Secondary Immune Response to Bacteriophage T1 in the Shore Crab, Carcinus maenas. Nature 203, 775 (1964). https://doi.org/10.1038/203775a0
Published:
Issue Date:
DOI: https://doi.org/10.1038/203775a0
This article is cited by
-
An attempt to immunize the blue crab,callinectes sapidus, with vertebrate red blood cells
Experientia (1973)
-
Untersuchungen zur humoralen Immunit�t bei Pyrrhocoris apterus L. und Galleria mellonella F.
Zeitschrift f�r Vergleichende Physiologie (1968)
-
Comparative immunological studies with the oyster,Crassostrea virginica
In Vitro (1967)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.