Abstract
THE effect of hydrocortisone on immune lysis was examined by titrating guinea pig complement in the presence of various concentrations of the steroid. Sheep erythrocytes, sensitized with rabbit anti-sheep cell hæmolysin, were used as the indicator system for complement activity; a 50 per cent lysis end point was used. Complement activity was not detectable in the presence of 5 mg/ml. hydrocortisone; the titre was reduced significantly by concentrations as low as 0.01 mg/ml.
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JENNINGS, J., TAYLOR, G. Effect of Hydrocortisone Hemi-succinate on Immune Lysis of Sheep Erythrocytes. Nature 203, 661 (1964). https://doi.org/10.1038/203661a0
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DOI: https://doi.org/10.1038/203661a0
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