Abstract
PROTEINS of the lens tissue of the eye have been extensively examined because of their relationship with cataract formation. In all forms of cataract a decrease was found in the total amount of lens proteins as compared with normal lens of the same age1. Changes in the proportion of the soluble proteins of the lens measured by electrophoresis have been reported in different kinds of cataract; but, according to van Heyningen2, no consistent patterns have emerged from these investigations. The work recorded here was carried out to determine the behaviour on paper electrophoresis of soluble lens proteins of the rat, as well as the possible changes in the proportion of the different fractions during lactose feeding.
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References
Pirie, A., and van Heyningen, R., Biochemistry of the Eye (Blackwell, Oxford, 1956).
van Heyningen, R., The Eye, edit. by Davson, H., 1, 213 (Academic Press, New York and London, 1962).
Korc, I., and Calcagno, M., Nature, 197, 690 (1963).
Wood, D. C., Massi, L., and Solomon, E. L., J. Biol. Chem., 234, 329 (1959).
François, J., Rabaey, M., Wieme, R. J., and Neetens, A., Ann. d'Ocul, 187, 37 (1954).
Korc, I., Galactosemia clínica y experimental (Ministerio de Instrucción Pública y Previsión Social, Montevideo, 1963).
Korc, I., and Calcagno, M. (to be published).
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KORC, I., SOBA, N., HIERRO, J. et al. Paper Electrophoresis of Soluble Lens Proteins in Lactose-fed Rats. Nature 203, 649–650 (1964). https://doi.org/10.1038/203649b0
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DOI: https://doi.org/10.1038/203649b0
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