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Effect of γ-Radiation on Deoxynucleoprotein acting as a Primer in RNA Synthesis

Abstract

IT has been found1 that on irradiation of calf-thymus deoxynucleoprotein (DNP) the major part of the radiation damage occurs on the protein moiety of the DNP and that, in fact, the DNA itself is largely protected from the effects of radiation. This would be in agreement, for example, with the structure of DNP as proposed by Wilkins2. Since it has been suggested that the protein (histone) in DNP is a regulator of RNA synthesis and thus of protein formation3, it seemed of interest to examine the effects of radiation on DNP and DNA when acting as primers for RNA synthesis.

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References

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WEISS, J., WHEELER, C. Effect of γ-Radiation on Deoxynucleoprotein acting as a Primer in RNA Synthesis. Nature 203, 291–292 (1964). https://doi.org/10.1038/203291b0

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