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Inhibition of Thrombin and of Fibrin Polymerization, Two Activities derived from Plasmin-digested Fibrinogen

Abstract

As was previously shown in our laboratory1, the clotting of fibrinogen initiated by one proteolytic enzyme (thrombin) is specifically inhibited by the products resulting from the action of another proteolytic enzyme (plasmin) on the same substrate.

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References

  1. Niewiarowski, S., and Kowalski, E., Trans. Sixth Congr. Europ. Soc. Haem. Copenhagen 1957, 560 (S. Karger, Basel, 1957).

  2. Buluk, K., and Januszko, T., Post. Hig. Med. Dośw., 12, 91 (1958).

    CAS  Google Scholar 

  3. Kowarzyk, H., Glogowska, I., and Szymk, S., Arch. Immun. Teraplii Dośw., 9, 341 (1961).

    CAS  Google Scholar 

  4. Triantaphyllopoulos, D. C., Amer. J. Physiol., 200, 771 (1961).

    CAS  PubMed  Google Scholar 

  5. Latallo, Z. S., Fletcher, A. P., Alkjaersig, N., and Sherry, S., Amer. J. Physiol., 202, 681 (1962).

    CAS  PubMed  Google Scholar 

  6. Fletcher, A. P., Alkjaersig, N., and Sherry, S., J. Clin. Invest., 41, 896 (1962).

    Article  CAS  Google Scholar 

  7. Alkjaersig, N., Fletcher, A. P., and Sherry, S., J. Clin. Invest., 41, 917 (1962).

    Article  CAS  Google Scholar 

  8. Bang, N. U., Fletcher, A. P., Alkjaersig, N., and Sherry, S., J. Clin. Invest., 41, 935 (1962).

    Article  CAS  Google Scholar 

  9. Budzyński, A. Z., Latallo, Z. S., Lipiński, B., and Kowalski, E., Bull. Pol. Acad. Sci. (in the press).

  10. Latallo, Z. S., Fletcher, A. P., Alkjaersig, N., and Sherry, S., Amer. J. Physiol., 202, 675 (1962).

    CAS  PubMed  Google Scholar 

  11. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, J., J. Biol. Chem., 193, 265 (1951).

    CAS  Google Scholar 

  12. Niewiarowski, S., Kowalski, E., and Stachurska, J., Acta Biochem. Polon., 6, 43 (1959).

    CAS  Google Scholar 

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LATALLO, Z., BUDZYŃSKI, A., LIPIŃSKI, B. et al. Inhibition of Thrombin and of Fibrin Polymerization, Two Activities derived from Plasmin-digested Fibrinogen. Nature 203, 1184–1185 (1964). https://doi.org/10.1038/2031184a0

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