Abstract
THE human tumour transplanted in the cheek pouch of the Syrian hamster has proved to be a useful tool for the examination of potential anti-tumour agents1,2. What appears to be an obvious advantage in using transplantable human tumours over transplantable animal tumours in chemotherapy investigations lies in the fact that a given compound can be assayed on cells of human origin growing in an in vivo system. However, at least two conditions would have to be fulfilled prior to making such a comparison: (1) transplanted human tumours should not undergo profound changes in their biological properties; (2) the host should not alter the effect of the tested agents on the human cells.
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CARDINALI, G., CARDINALI, G. & HANDLER, A. Effect of Colchicine on Human Tumours transplanted in Cheek Pouch of Syrian Hamster. Nature 203, 90–92 (1964). https://doi.org/10.1038/203090b0
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DOI: https://doi.org/10.1038/203090b0
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