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Occurrence of Urinary Calculi in Rats exposed to High Concentrations of Oxygen with Added Carbon Dioxide

Abstract

In the course of an investigation1 of the pulmonary responses of animals exposed to high concentrations of oxygen at atmospheric pressure (OAP) and to high concentrations of oxygen at atmospheric pressure to which 9–13 per cent carbon dioxide was added (OAP + CO2), discrete, amorphous, non-crystalline masses were found in the urinary bladder at autopsy.

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References

  1. DeClement, F. A., and Smith, C. W., Fed. Proc., 21, 444 (1962).

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  2. Smith, C. W., Lehan, P. H., and Monks, J. J., J. App. Physiol., 18, 849 (1963).

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  3. McGaughey, C., Nature, 192, 1267 (1961).

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SMITH, C., DECLEMENT, F. Occurrence of Urinary Calculi in Rats exposed to High Concentrations of Oxygen with Added Carbon Dioxide. Nature 203, 85–86 (1964). https://doi.org/10.1038/203085a0

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