Abstract
RIFAMYCINS are new antibiotics1,2 having a marked inhibitory effect on the growth of many Gram-positive bacteria, including staphylococci3,4, and have already been shown to affect bacterial respiration5. In this communication some results are reported concerning the effect of rifamycin SV and rifamycin M14 on the incorporation of amino-acids into protein by cell-free extracts of B. subtilis strain A.T.C.C. 6633.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Sensi, P., Greco, A. M., and Ballotta, R., Antibiotics Annual, 262 (1959–60).
Sensi, P., Ballotta, R., and Gallo, G. G., Il Farmaco, 16, 165 (1961).
Sensi, P., Margalith, P., and Timbal, M. T., Il Farmaco, Sci. ed., 14, 146, (1959).
Furesz, S., and Scotti, R., Antibiotics Annual, 285 (1959–60).
In the press.
Bücher, T., and Pfleiderer, G., Methods in Enzymology, 1, 435 (Acad. Press, Inc., New York, 1955).
Tissières, A., Schlessinger, D., and Gros, F., Proc. U.S. Nat. Acad. Sci., 46, 1450 (1960).
Matthaei, H. J., and Nirenberg, M. W., Proc. U.S. Nat. Acad. Sci., 47, 1580 (1961).
Demoss, G. A., and Novelli, G. D., Biochim. Biophys. Acta, 22, 49 (1956).
Boman, H. G., and Svensson, I., Nature, 191, 674 (1961).
Berg, P., Bergmann, F. H., Ofengand, J., and Dieckman, H., J. Biol. Chem., 236, 1726 (1961).
Marmur, J., J. Mol. Biol., 3, 208 (1961).
Ofengand, J., and Haselkorn, R., Biochem. Biophys. Res. Commun., 6, 469 (1961–62).
Rendi, R., and Ochoa, S., J. Biol. Chem., 237, 3711 (1962).
Franklin, T. J., Biochem. J., 87, 449 (1963).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
FRONTALI, L., LEONI, L. & TECCE, G. Action of Rifamycin on Incorporation of Amino-acids into Protein in Cell-free Systems from B. subtilis. Nature 203, 84–85 (1964). https://doi.org/10.1038/203084b0
Published:
Issue Date:
DOI: https://doi.org/10.1038/203084b0
This article is cited by
-
Effect of rifampicin on tryptophanase induction in normal and rifampicin-resistantVibrio el tor
Folia Microbiologica (1977)
-
Inhibition of Rodent Malaria in Mice by Rifampicin
Nature (1970)
-
Selective Inhibition of Vaccinia Virus by the Antibiotic Rifampicin
Nature (1969)
-
Mutant of E. coli containing an Altered DNA-dependent RNA Polymerase
Nature (1968)
-
Rifamycins LXI: In vivo inhibition of RNA synthesis by rifamycins
Experientia (1968)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.