Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Biochemical Pathology of Acute Hepatic Adenosinetriphosphate Deficiency

Nature volume 203, pages 34–40 (1964)Cite this article

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Dyer, H. M., J. Biol. Chem., 124, 519 (1938).

    Article  CAS  Google Scholar 

  2. Farber, E., Adv. Cancer Res., 7, 383 (1963).

    Article  CAS  PubMed  Google Scholar 

  3. Stekol, J. A., Adv. Enzymol., 25, 369 (1963).

    Google Scholar 

  4. Farber, E., Simpson, M. V., and Tarver, H., J. Biol. Chem., 182, 91 (1950).

    Article  CAS  Google Scholar 

  5. Koch-Weser, D., Farber, E., and Popper, H., Amer. Med. Assoc. Arch. Path., 51, 498 (1951).

    CAS  Google Scholar 

  6. Jensen, D., Chaikoff, I. L., and Tarver, H., J. Biol. Chem., 192, 395 (1951).

    Article  CAS  PubMed  Google Scholar 

  7. Horning, M. G., Earle, M. J., and Maling, H. M., Biochim. Biophys. Acta, 56, 175 (1962).

    Article  CAS  PubMed  Google Scholar 

  8. Arvidson, G., and Olivecrona, T., Acta Physiol. Scand., 55, 303 (1962).

    Article  CAS  PubMed  Google Scholar 

  9. Farber, E., Koch-Weser, D., and Popper, H., Endocrinology, 48, 205 (1951).

    Article  CAS  PubMed  Google Scholar 

  10. Farber, E., and Segaloff, A., J. Biol. Chem., 216, 471 (1955).

    Article  CAS  PubMed  Google Scholar 

  11. Simpson, M. V., Farber, E., and Tarver, H., J. Biol. Chem., 182, 81 (1950).

    Article  CAS  Google Scholar 

  12. Farber, E., and Corban, M. S., J. Biol. Chem., 233, 625 (1958).

    Article  CAS  PubMed  Google Scholar 

  13. Simmonds, S., Keller, E. B., Chandler, J. P., and du Vigneaud, V., J. Biol. Chem., 183, 191 (1950).

    Article  CAS  Google Scholar 

  14. Siekevitz, P., and Greenberg, D. M., J. Biol. Chem., 186, 275 (1950).

    Article  CAS  PubMed  Google Scholar 

  15. Farber, E., Fed. Proc., 14, 402 (1955).

    Google Scholar 

  16. Farber, E., Bull. Tulane Univ. Med. Fac., 14, 71 (1955).

    CAS  PubMed  Google Scholar 

  17. Farber, E., Amer. Med. Assoc. Arch. Path., 67, 1 (1959).

    CAS  Google Scholar 

  18. Shull, K. H., J. Biol. Chem., 237, PC1734 (1962).

  19. Stekol, J. A., Mody, U., Bedrak, E., Keller, S., and Perry, J., Fed. Proc., 19, 37 (1960).

    Google Scholar 

  20. Villa-Trevino, S., Shull, K. H., and Farber, E., J. Biol. Chem., 238, 1757 (1963).

    Article  CAS  PubMed  Google Scholar 

  21. Stekol, J. A., Anderson, E. P., Hsu, P. T., and Weiss, S., Abst. Amer. Chem. Soc., Cincinnati, 4 C (1955).

  22. Cantoni, G. L., J. Biol. Chem., 189, 745 (1951).

    Article  CAS  PubMed  Google Scholar 

  23. Shapiro, S. K., and Schlenk, F., Adv. Enzymol., 22, 237 (1960).

    CAS  Google Scholar 

  24. Maibauer, D., Naunyn-Schmiedeberg's Arch. exp. Path. Pharmak., 232, 234 (1957).

    Article  CAS  Google Scholar 

  25. Hutterer, F., Fitschen, W., and Popper, H., Brit. J. Exp. Pathol., 42, 187 (1951).

    Google Scholar 

  26. Thomas, M., and Farber, E. (unpublished work).

  27. Shull, K. H. (unpublished work).

  28. Schmidt, G., Seraidarian, K., Greenbaum, L. M., Hickey, M. D., and Thannhauser, S. J., Biochim. Biophys. Acta, 20, 135 (1956).

    Article  CAS  PubMed  Google Scholar 

  29. Farber, E., and Castillo, A. E., Fed. Proc., 22, 370 (1963).

    Google Scholar 

  30. de la Haba, G., and Cantoni, G. L., J. Biol. Chem., 234, 603 (1959).

    Article  CAS  PubMed  Google Scholar 

  31. Villa-Trevino, S., and Farber, E., Biochim. Biophys. Acta, 61, 649 (1962).

    CAS  Google Scholar 

  32. Keller, E. B., and Zamecnik, F., J. Biol. Chem., 221, 45 (1956).

    Article  CAS  PubMed  Google Scholar 

  33. Nathans, D., and Lipmann, F., Proc. U.S. Nat. Acad. Sci., 47, 497 (1961).

    Article  ADS  CAS  Google Scholar 

  34. Bishop, J. O., and Schweet, R. S., Biochim. Biophys. Acta, 54, 617 (1961).

    Article  CAS  PubMed  Google Scholar 

  35. Hultin, T., and von der Decken, A., in Protein Biosynthesis, edit. by Harris, R. J., 83 (Academic Press, London, 1961).

    Google Scholar 

  36. Takanami, M., Biochim. Biophys. Acta, 51, 85 (1961).

    Article  CAS  PubMed  Google Scholar 

  37. Takanami, M., and Okamoto, T., Biochim. Biophys. Acta, 44, 379 (1960).

    Article  CAS  PubMed  Google Scholar 

  38. Fessenden, J. M., and Moldave, K., Biochem., 1, 485 (1962).

    Article  CAS  Google Scholar 

  39. Fessenden, J. M., and Moldave, K., J. Biol. Chem., 238, 1479 (1963).

    Article  CAS  PubMed  Google Scholar 

  40. Lipman, F., in Progress in Nucleic Acid Research, edit. by Davidson, J. N., and Cohn, W. E., 135 (Academic Press, New York, 1963).

    Google Scholar 

  41. Tissiéres, A., Schlessinger, D., and Gros, F., Proc. U.S. Nat. Acad. Sci., 46, 1450 (1960).

    Article  ADS  Google Scholar 

  42. Risebrough, R. W., Tissières, A., and Watson, J. D., Proc. U.S. Nat. Acad. Sci., 48, 430 (1962).

    Article  ADS  CAS  Google Scholar 

  43. Spyrides, G., and Lipmann, F., Proc. U.S. Nat. Acad. Sci., 48, 1977 (1962).

    Article  ADS  CAS  Google Scholar 

  44. Barondes, S. H., and Nirenberg, M. W., Science, 138, 810, 813 (1962).

    Article  ADS  CAS  PubMed  Google Scholar 

  45. Watson, J. D., Science, 140, 17 (1963).

    Article  ADS  CAS  PubMed  Google Scholar 

  46. Gilbert, W., J. Mol. Biol., 6, 374 (1963).

    Article  CAS  PubMed  Google Scholar 

  47. Staehelin, T., Brinton, C., Wettstein, F. O., and Noll, H., Nature, 199, 865 (1963).

    Article  ADS  CAS  PubMed  Google Scholar 

  48. Wettstein, F. O., Staehelin, T., and Noll, H., Nature, 197, 430 (1963).

    Article  ADS  CAS  PubMed  Google Scholar 

  49. Staehelin, T., Wettstein, F. O., and Noll, H., Science, 140, 180 (1963).

    Article  ADS  CAS  PubMed  Google Scholar 

  50. Noll, H., Staehelin, T., and Wettstein, F. O., Nature, 198, 632 (1963).

    Article  ADS  Google Scholar 

  51. Korner, A., and Munro, A. J., Biochem. Biophys. Res. Comm., 11, 235 (1963).

    Article  CAS  Google Scholar 

  52. Marks, P. A., Burka, E. R., and Schlessinger, D., Proc. U.S. Nat. Acad. Sci., 48, 2163 (1962).

    Article  ADS  CAS  Google Scholar 

  53. Warner, J. R., Rich, A., and Hall, C., Science, 138, 1399 (1962).

    Article  ADS  CAS  PubMed  Google Scholar 

  54. Warner, J. R., Knopf, P. M., and Rich, A., Proc. U.S. Nat. Acad. Sci., 49, 122 (1963).

    Article  ADS  CAS  Google Scholar 

  55. Gierer, A., J. Mol. Biol., 6, 148 (1963).

    Article  CAS  PubMed  Google Scholar 

  56. Marks, P. A., Rifkind, R. A., and Danon, D., Proc. U.S. Nat. Acad. Sci., 50, 336 (1963).

    Article  ADS  CAS  Google Scholar 

  57. Penmann, S., Scherrer, K., Becker, Y., and Darnell, J. E., Proc. U.S. Nat. Acad. Sci., 49, 654 (1963).

    Article  ADS  Google Scholar 

  58. Goodman, H. M., and Rich, A., Nature, 199, 318 (1963).

    Article  ADS  CAS  PubMed  Google Scholar 

  59. Zimmerman, E. F., Biochem. Biophys. Res. Comm., 11, 301 (1963).

    Article  CAS  PubMed  Google Scholar 

  60. Villa-Trevino, S., and Farber, E. (unpublished results).

  61. Villa-Trevino, S., Shull, K. H., and Farber, E., Fed. Proc., 22, 237 (1963).

    Google Scholar 

  62. Villa-Trevino, S., Staehelin, T., Wettstein, F. O., Noll, H., and Farber, E. (unpublished results).

  63. Hurwitz, J., Furth, G. J., Malamy, M., and Alexander, M., Proc. U.S. Nat. Acad. Sci., 48, 1222 (1962).

    Article  ADS  CAS  Google Scholar 

  64. Kahan, E., Kahan, F. M., and Hurwitz, J., J. Biol. Chem., 238, 2491 (1963).

    Article  CAS  PubMed  Google Scholar 

  65. Levinthal, C., Keynan, A., and Higa, A., Proc. U.S. Nat. Acad. Sci., 48, 1631 (1962).

    Article  ADS  CAS  Google Scholar 

  66. Reich, F., Franklin, R. M., Shatkin, A. J., and Tatum, E. L., Proc. U.S. Nat. Acad. Sci., 48, 1238 (1962).

    Article  ADS  CAS  Google Scholar 

  67. Harbers, E., and Muller, W., Biochem. Biophys. Res. Comm., 7, 107 (1962).

    Article  CAS  PubMed  Google Scholar 

  68. Tamaoki, T., and Muller, G. C., Biochem. Biophys. Res. Comm., 9, 451 (1962).

    Article  CAS  PubMed  Google Scholar 

  69. Goldberg, I. H., and Rabinovitz, M., Science, 136, 315 (1962).

    Article  ADS  CAS  PubMed  Google Scholar 

  70. Merits, I., Biochem. Biophys. Res. Comm., 10, 254 (1963).

    Article  CAS  PubMed  Google Scholar 

  71. Yarmolinsky, M. B., and de la Haba, G. L., Proc. U.S. Nat. Acad. Sci., 45, 1721 (1959).

    Article  ADS  CAS  Google Scholar 

  72. Morris, A., and Schweet, R., Biochim. Biophys. Acta, 47, 415 (1961).

    Article  CAS  PubMed  Google Scholar 

  73. Hultin, T., Biochim. Biophys. Acta, 51, 219 (1961).

    Article  Google Scholar 

  74. Allen, D. W., and Zamecnik, P. C., Biochim. Biophys. Acta, 55, 865 (1962).

    Article  CAS  PubMed  Google Scholar 

  75. Nathan, D., von Ehrenstein, G., Munro, R., and Lipmann, F., Fed. Proc., 21, 127 (1962).

    Google Scholar 

  76. Lanz, R., and Farber, E. (unpublished results).

  77. Chantrenne, H., Adv. Enzymol., 24, 1 (1962).

    CAS  Google Scholar 

  78. Farber, E., Lombardi, B., and Castillo, A. E., Lab. Invest., 12, 873 (1963).

    CAS  PubMed  Google Scholar 

  79. Lombardi, B., and Recknagel, R. O., Amer. J. Path., 40, 571 (1962).

    CAS  PubMed  PubMed Central  Google Scholar 

  80. Lombardi, B., Villa-Trevino, S., Shull, K. H., and Farber, E. (unpublished results).

  81. Recknagel, R. O., Lombardi, B., and Schotz, M. C., Proc. Soc. Exp. Biol. Med., 104, 608 (1960).

    Article  CAS  PubMed  Google Scholar 

  82. Recknagel, R. O., and Lombardi, B., J. Biol. Chem., 235, 564 (1961).

    Article  Google Scholar 

  83. Lombardi, B., and Recknagel, R. O., Fed. Proc., 20, 289 (1961).

    Google Scholar 

  84. Harris, P. M., and Robinson, D. S., Biochem. J., 80, 352 (1961).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  85. Borgstrom, B., and Olivecrona, T., J. Lipid Res., 2, 263 (1961).

    Article  CAS  Google Scholar 

  86. Byers, S. O., and Friedman, M., Amer. J. Physiol., 198, 629 (1960).

    Article  CAS  PubMed  Google Scholar 

  87. Laurell, S., Acta Physiol. Scand., 46, 97 (1959).

    Article  CAS  PubMed  Google Scholar 

  88. Stein, Y., and Shapiro, B., Amer. J. Physiol., 196, 1238 (1959).

    Article  CAS  PubMed  Google Scholar 

  89. Feinberg, H., Rubin, L., Hill, R., Entenmann, C., and Chaikoff, I. L., Science, 120, 317 (1954).

    Article  ADS  CAS  PubMed  Google Scholar 

  90. Robinson, D. S., and Harris, P. M., Biochem. J., 80, 361 (1961).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  91. Bjornstad, P., and Bremer, J., Acta Chem. Scand., 17, 903 (1963).

    Article  Google Scholar 

  92. Haft, D. E., Roheim, P. S., White, A., and Eder, H. A., J. Clin. Invest., 41, 842 (1962).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  93. Marsh, J. B., Fed. Proc., 17, 270 (1958).

    Google Scholar 

  94. Marsh, J. B., and Whereat, A. F., J. Biol. Chem., 234, 3196 (1959).

    Article  CAS  PubMed  Google Scholar 

  95. Radding, C. M., and Steinberg, D., J. Clin. Invest., 39, 1560 (1960).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  96. Radding, C. M., Bragdon, J. H., and Steinberg, D., Biochim. Biophys. Acta, 30, 443 (1958).

    Article  CAS  PubMed  Google Scholar 

  97. Dianzani, M. U., Biochem. J., 65, 116 (1957).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  98. Smuckler, E. A., Iseri, O. A., and Benditt, E. P., Biochem. Biophys. Res. Comm., 5, 270 (1961).

    Article  CAS  Google Scholar 

  99. Smuckler, E. A., Iseri, O. A., and Benditt, E. P., J. Exp. Med., 116, 55 (1962).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  100. Robinson, D. S., and Seakins, A., Biochem. J., 82, 9P (1962).

    Article  CAS  Google Scholar 

  101. Robinson, D. S., and Seakins, A., Biochim. Biophys. Acta, 62, 163 (1962).

    Article  CAS  PubMed  Google Scholar 

  102. Kinney, T. D., Kaufman, N., and Klavins, J. V., Amer. J. Path., 43, 16a (1963).

    Google Scholar 

  103. Marroquin, F., and Farber, E. (unpublished results).

  104. Gordon, S., Villa-Trevino, S., and Farber, E. (unpublished results).

  105. Racker, E., Adv. Enzymol., 23, 323 (1961).

    CAS  Google Scholar 

  106. Scholtissek, C., Nature, 194, 353 (1963).

    Article  ADS  Google Scholar 

  107. Hiatt, H., J. Mol. Biol., 5, 217 (1962).

    Article  CAS  PubMed  Google Scholar 

  108. Georgiev, G. P., and Mantieva, V. E., Biochim. Biophys. Acta, 61, 153 (1962).

    CAS  PubMed  Google Scholar 

  109. Brenner, S., Jacob, F., and Meselson, M., Nature, 190, 576 (1961).

    Article  ADS  CAS  PubMed  Google Scholar 

  110. Gros, F., Hiatt, H., Gilbert, W., Kurland, C. G., Risebrough, R. W., and Watson, J. D., Nature, 190, 581 (1961).

    Article  ADS  CAS  PubMed  Google Scholar 

  111. Cheng, P.-Y., Biochim. Biophys. Acta, 53, 235 (1961).

    Article  CAS  Google Scholar 

  112. Sibatani, A., deKlolt, S. R., Allfrey, V. G., and Mirsky, A. E., Proc. U.S. Nat. Acad. Sci., 48, 471 (1962).

    Article  ADS  CAS  Google Scholar 

  113. Scherrer, K., and Darnell, J. E., Biochem. Biophys. Res. Comm., 7, 486 (1962).

    Article  CAS  PubMed  Google Scholar 

  114. Marks, P. A., Wilson, C., Kruh, J., and Gros, F., Biochem. Biophys. Res. Comm., 8, 9 (1962).

    Article  CAS  PubMed  Google Scholar 

  115. Scherrer, K., Latham, H., and Darnell, J. E., Proc. U.S. Nat. Acad. Sci., 49, 240 (1963).

    Article  ADS  CAS  Google Scholar 

  116. Magee, P. N., in The Scientific Basis of Medicine: Annual Review, 172 (Athlone Press, London, 1962).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania

    EMMANUEL FARBER,  KENNETH H. SHULL,  SAUL VILLA-TREVINO,  BENITO LOMBARDI & MOLLY THOMAS

Authors
  1. EMMANUEL FARBER
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. KENNETH H. SHULL
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. SAUL VILLA-TREVINO
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. BENITO LOMBARDI
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. MOLLY THOMAS
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

FARBER, E., SHULL, K., VILLA-TREVINO, S. et al. Biochemical Pathology of Acute Hepatic Adenosinetriphosphate Deficiency. Nature 203, 34–40 (1964). https://doi.org/10.1038/203034a0

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/203034a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing