IT is now known that a number of insect species which are resistant to insecticides possess effective means of detoxication in order to protect themselves from being exposed to the toxicant at the vital site1–3. One of these insects, Culex tarsalis Fresno strain, was shown to have developed a malathion Carboxyesterase3 with a very narrow substrate specificity against malathion analogues4. This agrees perfectly with the fact that this strain shows little cross-resistance to any other organophosphorus insecticides.
This is a preview of subscription content, access via your institution
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Rent or buy this article
Get just this article for as long as you need it
Prices may be subject to local taxes which are calculated during checkout
Lovell, J. B., and Kearns, C. W., J. Econ. Entomol., 52, 931 (1959).
Oppenoorth, F. J., Nature, 181, 425 (1958).
Matsumura, F., and Brown, A. W. A., J. Econ. Entomol., 54, 1176 (1961).
Dauterman, W. C., and Matsumura, F., Science, 138, 694 (1962).
Matsumura, F., and Hogendijk, C. J., Entomol. Exp. et App. (in the press).
Oppenoorth, F. J., Entomol. Exp. et App., 2, 216 (1959).
Oppenoorth, F. J., Entomol. Exp. et App., 2, 304 (1959).
Dauterman, W. C., and Main, A. R., Bull. Entomol. Soc. Amer., 8, 155 (1962).
Seume, F. W., and O'Brien, R. D., Toxicol. App. Pharmacol., 2, 495 (1960).
Seume, F. W., and O'Brien, R. D., J. Agric. Food Chem., 8, 36 (1960).
Oppenoorth, F. J., and Asperen, K. van, Entomol. Exp. et App., 4, 311 (1961).
Busvine, J. R., Entomol. Exp. et App., 2, 58 (1959).
Rights and permissions
About this article
Cite this article
MATSUMURA, F., DAUTERMAN, W. Effect of Malathion Analogues on a Malathionresistant Housefly Strain which possesses a Detoxication Enzyme, Carboxyesterase. Nature 202, 1356–1358 (1964). https://doi.org/10.1038/2021356b0
This article is cited by
Metabolism of organophosphorus insecticides
Archiv f�r Mikrobiologie (1972)
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.