NORMAL chromatograms of wide-range samples obtained under constant column inlet and outlet pressures give high narrow peaks and low wide peaks at short and long retention times respectively for equal concentrations; this observation is the basis of the theoretical plate value calculation. At longer retention times there is a risk of compounds remaining undetected. Temperature programming has been used to minimize this risk and enables wider range samples to be analysed; this technique also tends to equalize peak widths.
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CLARKE, S. Pressure-programmed Gas-liquid Partition Chromatography. Nature 202, 1106 (1964). https://doi.org/10.1038/2021106a0
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