Abstract
Toxic materials are obtained by oxidation of highly unsaturated fatty acids, and significant effects are produced by these products on biological systems. Methyl linoleate and methyl linolenate are readily oxidized on exposure to ultra-violet radiation to yield products which inhibit enzymatic reactions1 and cellular respiration2 and interrupt division of yeast cells3. Other consequences of the autoxidation of lipids are detailed in a recent symposium4. This communication deals with an in vivo response of the mouse liver to an aqueous extract of ultraviolet-irradiated linolenic acid.
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WARAVDEKAR, V., ANDERSON, H., SASLAW, L. et al. Hepatotropic Effect in Mice by an Aqueous Extract of Ultra-violet-irradiated Linolenic Acid. Nature 202, 1009 (1964). https://doi.org/10.1038/2021009a0
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DOI: https://doi.org/10.1038/2021009a0
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