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Effects of α-Methyl-norvaline on Synthesis of Hæmoglobin in the Area Vasculosa of the Chick Embryo

Nature volume 201, pages 832–833 (1964)Cite this article

Abstract

IN the course of investigations on the effects of amino-acid analogues on explanted two-day chick embryos, α-methyl-norvaline, which has a structure closely similar to both valine and leucine (Fig. 1), has been found to cause a reduction of the quantity of hæmoglobin formed in the area vasculosa. At the concentrations used in these experiments, there was no effect on other embryonic tissues, but in higher concentrations the analogue caused arrest of the heart-beat and subsequent death and disintegration of the embryonic axis.

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Authors and Affiliations

  1. Department of Anatomy and Embryology, University College, London

    ELIZABETH DEUCHAR & A. M. L. DRYLAND

Authors
  1. ELIZABETH DEUCHAR
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  2. A. M. L. DRYLAND
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DEUCHAR, E., DRYLAND, A. Effects of α-Methyl-norvaline on Synthesis of Hæmoglobin in the Area Vasculosa of the Chick Embryo. Nature 201, 832–833 (1964). https://doi.org/10.1038/201832b0

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