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Y-linkage in Man

Abstract

STERN1, analysing the evidence concerning the mode of inheritance of 16 traits which were suspected to be completely Y-linked in man, emphasized that in organisms with heterogamy of the male sex, complete Y -linkage of genes with full penetrance is characterized by: (a) occurrence of the trait in males only; (b) its re-occurrence in all sons of affected males; (c) the daughters of affected men being not only phenotypically normal but also, in addition, not having affected offspring. One of the traits discussed was hypertrichosis of the ears (hypertrichosis pinnæ auris2), and Stern criticized the original pedigree published by Tommasi3,4 on grounds of its having been based on unreliable hearsay evidence. He concluded that judgment on the mode of inheritance of this trait should be postponed until better evidence became available.

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References

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DRONAMRAJU, K. Y-linkage in Man. Nature 201, 424–425 (1964). https://doi.org/10.1038/201424b0

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