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Uptake and Metabolism of Noradrenaline in Acute Inflammation of Rabbit Skin induced by Ultra-violet Light

Abstract

THE origin of normally occurring catecholamines in the skin1 is unknown. Possibilities for uptake in the skin of circulating amines2 as well as a local synthesis in that tissue3,4 seem to exist. Furthermore, enzymatic breakdown in vitro of noradrenaline in the skin has recently been demonstrated5. In view of the well-known vasoactive properties of noradrenaline, it was thought of interest to study its uptake and metabolism in relation to the vascular reactions of inflamed skin.

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References

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MÖLLER, H. Uptake and Metabolism of Noradrenaline in Acute Inflammation of Rabbit Skin induced by Ultra-violet Light. Nature 201, 1233–1234 (1964). https://doi.org/10.1038/2011233a0

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