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Lymphatic Transport of Beta-glucuronidase during Hæmorrhagic Shock

Abstract

PROGRESSIVE autolysis of visceral cells is a feature of experimentally produced shock in animals. This death of individual cells is associated with disruption of sub-cellular cytoplasmic particles (lysosomes) with release and activation of degradative enzymes1,2. Intra- and extracellular components may become substrates for these circulating enzymes as metabolic acidosis and hypoxia damage other tissues.

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DUMONT, A., WEISSMANN, G. Lymphatic Transport of Beta-glucuronidase during Hæmorrhagic Shock. Nature 201, 1231–1232 (1964). https://doi.org/10.1038/2011231a0

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