Abstract
Thiessen and Nealey1 recently reported differences among five inbred strains of mice in behavioural reactivity and in adrenocortical activity, in response to taking blood counts and handling. On several measures, the C57BL/Crgl strain displayed greater sensitivity to the testing conditions than did other strains. Resting blood eosinophil-level was higher, test-retest reliability was higher and the correlation between resting-level and extent to which the second count differed from the initial count was greater. These findings corroborate the conclusion of Wragg and Speirs2 that the C57 genotype is maximally sensitive to measures of eosinopenic responses and, in addition, point out the value of the C57BL/Crgl strain for experimental purposes.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Thiessen, D. D., and Nealey, Vicki G., Endocrinol., 71, 267 (1962).
Wragg, L. E., and Speirs, R. S., Proc. Soc. Exp. Biol. Med., 80, 680 (1952).
Speirs, R. S., and Meyer, R. K., Endocrinol, 45, 403 (1949).
Comm. Stand. Nomen. Inbred Strains of Mice, Cancer Res., 20, 145 (1960).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
NEALEY, V., THIESSEN, D. Further Observations on Differences in Eosinopenia between Inbred Strains of Mice. Nature 201, 1055–1056 (1964). https://doi.org/10.1038/2011055b0
Issue Date:
DOI: https://doi.org/10.1038/2011055b0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
