Electrical Charge Density of Spleen Cells sensitized against L-strain Fibroblasts


IT has previously been shown that homologous and heterologous spleen cells, sensitized against L-strain fibroblasts, have a marked cytopathic effect on the fibroblasts in vitro1,2. It was thought useful to examine the electrical surface charge density of these sensitized spleen cells in view of the possible changes which occur at the cell surface during the process of sensitization. This communication presents such results obtained by cell electrophoresis.

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  1. 1

    Taylor, H. E., and Culling, C. F. A., Lab. Invest., 12, 884 (1963).

  2. 2

    Rosenau, W., and Moon, H. D., J. Nat. Cancer Inst., 27, 471 (1961).

  3. 3

    Vassar, P. S., Nature, 197, 1215 (1963).

  4. 4

    Eisenberg, S., Ben-Or, S., and Doljanski, F., Exp. Cell Res., 26, 451 (1962).

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VASSAR, P., TAYLOR, H. & CULLING, C. Electrical Charge Density of Spleen Cells sensitized against L-strain Fibroblasts. Nature 200, 691–692 (1963) doi:10.1038/200691b0

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