Abstract
RECENT evidence for the presence of carnitine in phospholipids of yolk sac has been given by Mehlman and Wolf1. Accordingly, it was proposed by these authors that phosphatidyl carnitine could represent a bound form of carnitine in avian tissue. In contrast to the results of Strack et al.2 and Hosein and Proulx3, their investigations failed to show the presence of any bound carnitine in the mammalian species. In this latter case, analyses were performed in the dialysable material obtained from trichloroacetic (TCA) extracts : no study was made on the TCA precipitates nor on the non-dialysable residues. It is quite conceivable that carnitine could have been present, in the fractions not investigated, either bound to or as a component of phospholipid.
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References
Mehlman, A. M., and Wolf, G., Arch. Biochem. and Biophys., 98, 146 (1962).
Strack, E., Otzsch, W., and Lorenz, I., Protides of the Biological Fluids, edit. by Peeters, H., 235 (Elsevier Publishing Co., Amsterdam, 1960).
Hosein, E. A., and Proulx, P., Nature, 187, 321 (1960).
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Linneweh, W. Z., Physiol. Chem., 181, 42 (1929).
Wolf, G., and Berger, C. R. A., Arch. Biochem. Biophys., 97, 360 (1961).
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PROULX, P. Bound Carnitine in Bovine Brain. Nature 200, 1210–1211 (1963). https://doi.org/10.1038/2001210a0
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DOI: https://doi.org/10.1038/2001210a0
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