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Changes of Dehydrogenase Activity during Transneuronal Atrophy

Abstract

ALTHOUGH the cytology of transneuronal atrophy in the lateral genieulate nucleus is well documented in cat1, cytochemical studies of transneuronal atrophy are lacking. In the cat there are 3 laminæ in each nucleus. Following unilateral enucleation, the neurones of the middle lamina of the ipsilateral lateral genieulate nucleus and the first and third lamina of the contralateral lateral genieulate nucleus undergo transneuronal atrophy. The opportunity of observing normal and atrophied laminse side by side permits an immediate appreciation of any cytochemical changes in the atrophied lamina with respect to the adjacent normal control lamina.

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References

  1. Cook, W. H., Walker, J. H., and Barr, M. L., J. Comp. Neural., 94, 267 (1951).

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KUPFER, C. Changes of Dehydrogenase Activity during Transneuronal Atrophy. Nature 200, 80–81 (1963). https://doi.org/10.1038/200080a0

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