Letter | Published:

Photodynamic Effect of Diidroquinidine on Isolated Hearts of Mammals

Naturevolume 199pages915916 (1963) | Download Citation



THE photodynamic action of diidroquinidine chloridrate on Paramecia, blood serum and isolated heart of a frog has been observed by Pace et al.1. Examination of this particular action of diidroquinidine on the isolated heart and the effect of some photodynamic substances (that is, hæmatoporphyrin) on the function of isolated hearts of mammals and amphibians2,3 suggested the opportunity of investigating the photodynamic effect of diidroquinidine on isolated mammal hearts by electrocardiographic technique.

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  1. 1

    Pace, G., Prino, G., and Santamaria, L., Atti Soc. Ital. Pat., 6, 797 (1959).

  2. 2

    Santamaria, L., Prino, G., and Pace, G., Atti Soc. Ital. Pat., 6, 843 (1959).

  3. 3

    Pace, G., Prino, G., and Santamaria, L., Il Farmaco, 3, 219 (1961).

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  1. Cattedra di Patologia Generale della Facoltà di Scienze, Università di Milano

    • G. PACE
    •  & W. PIERPAOLI


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