Letter | Published:

Antibacterial Activity of Herpes Simplex Virus grown in Tissue Culture

Naturevolume 199pages721722 (1963) | Download Citation



ANTIBACTERIAL substances have been recovered from bacteria, actinomycetes, fungi, lichens and seed plants1,2 but not from viruses. Gan and Warsa3 observed that the allantoic fluid of embryonated eggs infected with influenza virus possessed lytic activity against a variety of microorganisms, but concluded that this lytic factor was distinct from the virus itself. In the light of the observation that herpes simplex lesions around the nose and mouth rarely, if ever, become infected despite their heavy exposure to pathogenic strains of staphylococci, a study was undertaken to determine whether herpes simplex virus exerts any inhibitory effect on the growth of staphylococci and other bacteria.

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  1. 1

    Waksman, S. A., Microbial Antagonisms and Antibiotic Substances (N.Y. Commonwealth Fund, 1945).

  2. 2

    Florey, H. W., Chair, E., Heatley, M. A., Jennings, A. G., Sanders, A. G., Abraham, E. P., and Florey, M. E., Antibiotics (Oxford Medical Publications, 1949).

  3. 3

    Gan, K. H., and Warsa, R., Amer. J. Hyg., 69, 83 (1959).

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  1. Department of Microbiology, Mount Sinai Hospital, New York

    •  & BELLA SHORE


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