Abstract
WHILE interpreting the results of studies in women and the dual role of ‘Norethynodrel’, Rock describes it as ‘rebound effect’ possibly on the pituitary gland1. It has been shown that syntheses of gonadotrophins are affected by administration of ‘Norethynodrel’2,3. Our recent experiments on this rebound effect phenomenon and the results obtained have brought forth some new thoughts on the role of anterior pituitary gland in gonadotrophic hormone elaboration.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Rock, J., Garcia, C. R., and Pincus, G., Rec. Prog. Horm. Res., 13, 323 (1957).
Drill, V. A., Jap. J. Pharm., 11, 88 (1962).
Pincus, G., Proc. Symp. 19-Nor Steroids, Chicago, 105 (1957).
Holmes, R. L., and Mandl, A. M., J. Endocrinol., 24, 297 (1962).
Bayliss, W. M., and Starling, E. H., Proc. Roy. Soc., 73, 710 (1904).
Zuckerman, S., Lancet, i, 739 (1954).
Turner, C. D., General Endocrinology (Saunders, 1960).
Nelson, W. O., and Patanelli, D. J., First Intern. Conf. Endocrinol., Copenhagen, 905 (1960).
Burrows, H., Biological Actions of Sex Hormones (Cambridge, 1949).
Ramaswami, L. S., and Lakshman, A. B., Nature, 181, 1210 (1958).
Harris, G. W., Physiol. Rev., 28, 139 (1948).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
LAKSHMAN, A., NELSON, W. ‘Rebound Effect’ of Ovulation-inhibiting Steroid in Rats. Nature 199, 608–609 (1963). https://doi.org/10.1038/199608a0
Issue Date:
DOI: https://doi.org/10.1038/199608a0
This article is cited by
-
Vorverlegung, Verz�gerung und Hemmung der Ovulation
Archiv f�r Gyn�kologie (1965)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.