Letter | Published:

Stimulation by Rat Liver Ribonucleic Acid of Incorporation of Amino-acid into Rat Liver Ribosomes

Naturevolume 199pages489490 (1963) | Download Citation



THE discovery1 that ribonucleic acid (RNA) and synthetic polyribonucleotides stimulated the incorporation of amino -acids into protein-like material in cell-free system from E. coli has been followed by many reports2–6 of similar findings with systems from the same and other cells. Rat liver RNA was shown5 to stimulate amino-acid incorporation when added to an E. coli system and rat liver RNA and polyuridylic acid caused increased incorporation of phenylalanine in a rat-liver microsomal system6. We wish to report that polyuridylic acid and rat liver RNA stimulate incorporation of amino-acid with rat liver ribo-somes.

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  1. Department of Biochemistry, University of Cambridge

    • A. KORNER
    •  & A. J. MUNRO


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