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Changes of Coenzyme (TPN) Diaphorase and TPN-linked Dehydrogenase during Axonal Reaction of the Nerve Cell

Abstract

EXAMINATION of the axonal reaction of the nerve cell has revealed a high level of metabolic processes. Lipid, protein and RNA content1,2, increase and changes in the activity of various enzymes have been described1,3,5,6,8. Most of the histochemical investigations of the enzymes in this field were carried out on anterior horn cells or on dorsal root ganglia after cutting the sciatic nerve. A disadvantage of this is the normal variability of enzymatic activity, especially in the spinal ganglia. Difficulty is also encountered in cryostat material in differentiating a normal cell from a chromatolytic cell.

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KREUTZBERG, G. Changes of Coenzyme (TPN) Diaphorase and TPN-linked Dehydrogenase during Axonal Reaction of the Nerve Cell. Nature 199, 393–394 (1963). https://doi.org/10.1038/199393b0

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