Abstract
DURING recent years, evidence has been accumulating that cells often may discriminate between a substance that they synthesize and the same substance that is preformed and assimilated from the environment. This capacity to respond differently to a compound introduced from the extracellular fluid, as compared to that formed within the cell, may be attributable to the compartmentation of intracellular events.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Day, M., and Green, J. P., J. Physiol., 164, 227 (1962).
Day, M., and Green, J. P., Biochem. Pharmacol., 11, 1043 (1962).
Green, J. P., and Furano, A. V., Biochem. Pharmacol., 11, 1049 (1962).
White, T., J. Physiol., 152, 299 (1960).
Lilja, B., Lindell, S.-E., and Saldeen, T., J. Allergy, 31, 492 (1960).
Carlini, E. A., and Green, J. P., Brit. J. Pharmacol., 20, 264 (1963).
Riley, J. P., The Mast Cells (E. and S. Livingstone, London, 1959).
Lagunoff, D., and Benditt, E. P., Ann. N. Y. Acad. Sci., 103, 185 (1963).
Brown, D. D., Tomchick, R., and Axelrod, J., J. Biol. Chem., 234, 2948 (1959).
Westling, H., and Wetterqvist, H., Med. Exp., 7, 51 (1962).
Aziz, A. A., Biochem. J., 80, 50, P (1961).
Netter, K. H., Cohn, jun., V. A., and Shore, P. A., Amer. J. Physiol., 201, 224 (1961).
Özand, P., Narahara, H. T., and Cori, C. F., J. Biol. Chem., 237, 3037 (1962).
Cowie, D. B., and McLure, F. T., Biochim. Biophys. Acta, 31, 236 (1959).
Mandel, H. G., and Altman, R. L., J. Pharmacol. Exp. Therap., 133, 151 (1961).
Kandaswamy, T. S., and Henderson, J. F., Biochim. Biophys. Acta, 61, 86 (1962).
Lichtenstein, J., Barnes, H. D., and Cohen, S. S., J. Biol. Chem., 235, 457 (1960).
Beljanski, M., and Ochoa, S., Proc. U. S. Nat. Acad. Sci., 44, 494 (1958).
Mizuno, S., Etsuko, Y., Takahashi, H., and Maruo, B., Biochim. Biophys. Acta, 49, 369 (1961).
Robbins, P. W., Traut, R. R., and Lipmann, F., Proc. U.S. Nat. Acad. Sci., 45, 6 (1959).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
FURANO, A., GREEN, J. Differences in the Disposition of Endogenous and Exogenous Substances by Cells. Nature 199, 380–381 (1963). https://doi.org/10.1038/199380a0
Issue Date:
DOI: https://doi.org/10.1038/199380a0
This article is cited by
-
Aspects of histamine metabolism
Agents and Actions (1987)
-
Endogenous respiration and regulation in a primitive marine fungus
Archives of Microbiology (1980)
-
Histamine and its metabolism in mammals part II: Catabolism of histamine and histamine liberation
Agents and Actions (1975)
-
Methylhistamine and Histamine in the Urine of Women During the Elaboration of Œstrogen
Nature (1964)
-
Sterols in Neoplastic Cells
Nature (1964)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
