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Sedimentation Behaviour of Adenylsuccinase formed by Interallelic Complementation in Neurospora crassa

Nature volume 199, pages 304305 (20 July 1963) | Download Citation

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Abstract

IT has been reported1,2 that enzymes produced by interallelic complementation, including Neurospora adenylosuccinase3, are not generally identical in all properties with corresponding wild-type enzymes. One of the models proposed4 to explain this situation involves the formation of hybrid polymeric enzyme molecules. This concept has been given some support by observations of enzymes (and other specific proteins) of intermediate electrophoretic mobility5–14 produced under conditions favourable to hybridization in vivo or in vitro.

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Affiliations

  1. J. W. Gibbs Research Laboratories, Department of Biology, Yale University, New Haven, Conn.

    • C. W. H. PARTRIDGE
    •  & NORMAN H. GILES

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https://doi.org/10.1038/199304a0

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