Letter | Published:

Reduction by Chlorpromazine of Pylorus-ligation Ulcers in the Rat

Nature volume 199, page 1296 (28 September 1963) | Download Citation

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Abstract

RECENT research indicates that chlorpromazine is an effective inhibitor of gastric secretion1–3 and reduces starvation ulcers in mice4. This investigation was undertaken to determine quantitatively the extent of ulceration in the fore-stomach and glandular stomach of the pylorus-ligated rat after treatment with chlorpromazine.

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References

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Author information

Author notes

    • ROY N. TIEDE

    National Science Foundation Summer Science Trainee.

    • CARL J. PFEIFFER

    Present address: N.A.S.A. Ames Research Center, Moffett Field, California.

Affiliations

  1. Department of Physiology, Southern Illinois University, Carbondale, Illinois.

    • ROY N. TIEDE
    • , CARL J. PFEIFFER
    •  & GEORGE H. GASS

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DOI

https://doi.org/10.1038/1991296a0

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