Letter | Published:

Effect of Thyrotropin on Nucleic Acids and Protein Contents of the Thyroid

Naturevolume 199pages12031204 (1963) | Download Citation



IN a previous paper1 we reported the effect of single and repeated doses of thyrotropic hormone (TSH) on the contents of protein-bound iodine-131 (PB131I) in whole thyroids and their subcellular fractions, 1 h after administration of Na131I. The contents of protein, ribonucleic acids (RNA) and deoxyribonucleic acids (DNA) were analysed in thyroidal homogenates and fractions on similarly treated guinea pigs. The preliminary results of the latter investigations are reported here.

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  1. 1

    Pantić, V., and Ekholm, R., Nature, 198, 903 (1963).

  2. 2

    Schneider, W. C., J. Biol. Chem., 161, 293 (1945).

  3. 3

    Lowry, H. O., Rosebrough, N. J., Farr, A. L., and Randall, R. J., J. Biol. Chem., 193, 265 (1951).

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  1. Department of Anatomy, University of Gothenburg, Sweden

    • R. EKHOLM
    •  & V. PANTIĆ


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