Abstract
THE capacity of Staphylococcus aureus to produce disease resides in its ability to invade and persist in the body, and in its elaboration of toxic metabolites. Host-defensive mechanisms comprise the elaboration of antibodies which facilitate phagocytosis and intracellular destruction, and the elaboration of antitoxins. This communication reports identification of at least one antigen of the staphylococcal cell-wall which is critical for phagocytosis by human blood leucocytes.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Mudd, S., Lenhart, N. A., and deCourcy, jun., S. J., Fed. Proc., 21, 14 (1962).
Li, I. W., Mudd, S., and Kapral, F. A., J. Immunol., 90, 804 (1963).
Baddiley, J., and Davison, A. L., J. Gen. Microbiol., 24, 295 (1961).
Morse, S. I., J. Exp. Med., 116, 229 (1962).
Cohn, Z. A., and Morse, S. I., J. Exp. Med., 110, 419 (1959).
Yoshida, A., Hedén, C.-G., Cedergren, B., and Edebo, L., J. Biochem. Microbiol. Tech. Eng., 3, 151 (1961).
Yoshida, A., and Hedén, C.-G., J. Immunol., 88, 389 (1962).
Baddiley, J., Armstrong, J. J., and Buchanan, J. G., Biochem. J., 76, 610 (1960).
Baddiley, J., Buchanan, J. G., Martin, R. O., and RajBhandary, U. L., Biochem. J., 85, 49 (1962).
Baddiley, J., J. Roy. Inst. Chem., 86, 366 (1962).
Sanderson, A. R., Juergens, W. G., and Strominger, J. L., Biochem. Biophys. Res. Comm., 5, 472 (1961).
Nathenson, S. G., and Strominger, J. L., J. Biol. Chem., 237, 3839 (1962).
Sanderson, A. R., Strominger, J. L., and Nathenson, S. G., J. Biol. Chem., 237, 3603 (1962).
O'Brien, P. J., Glick, M. C., and Zilliken, F., Biochim. Biophys. Acta, 37, 357 (1960).
Glick, M. C., Sall, T., Zilliken, F., and Mudd, S., Biochim. Biophys. Acta, 37, 361 (1960).
Glick, M. C., Chen, I.-W., and Zilliken, F., J. Biol. Chem., 237, 981 (1962).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
MUDD, S., YOSHIDA, A., LI, I. et al. Identification of a Somatic Antigen of Staphylococcus aureus Critical for Phagocytosis by Human Blood Leucocytes. Nature 199, 1200–1201 (1963). https://doi.org/10.1038/1991200a0
Issue Date:
DOI: https://doi.org/10.1038/1991200a0
This article is cited by
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
