Letter | Published:

Immunoglobulin Abnormalities of the Thymectomized Rat

Nature volume 199, pages 11991200 (21 September 1963) | Download Citation

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Abstract

WE have shown that the adult rat, thymectomized at birth, has a global defect in delayed hypersensitive responses correlated with a depletion of small lymphocytes from blood, lymph nodes and spleen1. The deficiency in antibody mediated responses, in contrast, is selective. The nature of this latter defect has not been clarified. It has been shown that plasma cell and serum γ-globulin levels are normal in thymectomized rats2.

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Affiliations

  1. Institut de Recherches Scientifiques sur le Cancer, Villejuif (Seine), France.

    • BARRY G. ARNASON
    • , CHRISTIANE DE VAUX ST. CYR
    •  & PIERRE GRABAR

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DOI

https://doi.org/10.1038/1991199a0

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