Letter | Published:

Formation of Extra Nerve-muscle Junctions in Innervated Muscle

Naturevolume 199pages11911192 (1963) | Download Citation



IF a foreign motor nerve is connected to a normally innervated muscle, the nerve fibres grow into it but do not establish intimate contact with muscle fibres, and are unable to transmit impulses to them. On the other hand, if the muscle fibres are deprived of their normal innervation a foreign nerve will establish functional connexions with them1–3.

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    Elsberg, C. A., Science, 45, 318 (1917).

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    Aitken, J. T., J. Anat., 84, 38 (1950).

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    Guth, L., and Zalewski, A. A., Exp. Neurol., 7, 316 (1963).

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    Miledi, R., Nature, 193, 281 (1962).

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    Koenig, J., C.R. Acad. Sci., Paris, 256, 2918 (1963).

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    Harrison, R. G., J. Exp. Zool., 9, 787 (1910).

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    Miledi, R., J. Physiol., 154, 190 (1960).

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    Katz, B., Johns Hopkins Hosp. Bull., 102, 275 (1958).

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  1. Department of Biophysics, University College, London

    • R. MILEDI


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