Letter | Published:

Nicotinamide-adenine Dinucleotides, Adenosine Diphosphate and Adenosine Triphosphate Content of Tissues infected by Tobacco Mosaic Virus

Naturevolume 199pages11161117 (1963) | Download Citation



THE physiology of virus-infected plant tissues is of interest in that an understanding of the processes underlying the development of disease symptoms is dependent on a knowledge of changes in the host tissue metabolism induced by virus-infection. An approach to this problem is a consideration of nucleotide-levels in tissues infected by virus. The formation of tobacco mosaic virus (TMV) may give lower nucleotide-levels in the host tissue as a result of the utilization of nucleotides in virus–ribonucleic acid synthesis. This is of particular significance with regard to the adenosine nucleotides, adenosine diphosphate (ADP), adenosine triphosphate (ATP), nicotinamide-adenine di-nucleotide (NAD) and nicotinamide-adenine dinucleotide phosphate (NADP), all of which are concerned in the regulation of the intermediary metabolism of the host-tissue1.

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  1. 1

    Krebs, H., in Regulation of Cell Metabolism, edit. by Wolstenholme, G. E. W., and O'Conner, C. M. (Churchill, 1959).

  2. 2

    Merrett, M. J., Physiol. Plant., 15, 465 (1962).

  3. 3

    Owen, P. C., Ann. App. Biol., 43, 265 (1955).

  4. 4

    Merrett, M. J., Ann. Bot., N.S., 24, 223 (1960).

  5. 5

    Merrett, M. J. (in preparation).

  6. 6

    Morel, G., Ann. epiphyt. (N.S.), 14, 1 (1948).

  7. 7

    Kassanis, B., Virology, 4, 5 (1957).

  8. 8

    Slater, T. F., and Sawyer, B., Nature, 193, 454 (1962).

  9. 9

    Kornberg, A., in Methods in Enzymology, edit. by Colowick, S. P., and Kaplan, N. O., 3, 878 (Academic Press, Inc., 1957).

  10. 10

    Strehler, B. L., and McElroy, W. D., in Methods in Enzymology, edit. by Colowick, S. P., and Kaplan, N. O., 3, 871 (Academic Press, Inc., 1957).

  11. 11

    Yamaguchi, A., and Hirai, T., Virus (Osaka), 6, 1 (1955).

  12. 12

    Solmosy, F., and Farkas, G. L., Nature, 195, 835 (1962).

  13. 13

    Sunderland, D. W., and Merrett, M. J., (in preparation).

  14. 14

    Yamaguchi, A., and Hirai, T., Phytopath., 49, 447 (1959).

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  1. Department of Biological Sciences, Institute of Technology, Bradford

    •  & M. J. MERRETT


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