Abstract
THE characteristic histological abnormalities of toxæmia of pregnancy (pre-eclampsia) are found in glomeruli and consist mainly of endothelial swelling1. Electron microscopic studies of renal biopsies have confirmed that the main change is marked swelling of endothelial and inter-capillary cells, and have shown in addition the frequent occurrence of dark, granular material deposited between the swollen endothelial cells or along the basement membranes2,3.
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VASSALLI, P., SIMON, G. & ROUILLER, C. Production of Ultra-structural Glomerular Lesions resembling those of Toxæmia of Pregnancy by Thromboplastin Infusion in Rabbits. Nature 199, 1105–1106 (1963). https://doi.org/10.1038/1991105a0
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DOI: https://doi.org/10.1038/1991105a0
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