Letter | Published:

Interference Experiments relating to whether Tobacco Mosaic Virus and Cucumber Viruses 3 and 4 are Strains of the same Virus

Naturevolume 199pages10151016 (1963) | Download Citation



THE problem of whether cucumber viruses 3 and 4 (CVS, CV4) and tobacco mosaic virus (TMV) are different viruses or strains of the same virus has been examined in detail by Knight1. On the basis of several criteria such as host-range, chemical composition, electron microscope morphology, etc., he concluded that they were different viruses. However, two criteria, serology and the ability to exhibit cross-protection, still support the idea that they are strains of the same virus. In regard to cross-protection, it was first found by Fulton2 that prior infection of cucumber by CV3 and CV4 did not protect against subsequent TMV infection, but later Rochow5 was able to demonstrate a high degree of protection. Apparently, the difference between Fulton's and Rochow's experiments is shown in the length of time the plant is allowed to sustain a CV3 and CV4 infection before it is challenged by a second inoculation with TMV.

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  1. 1

    Knight, C. A., Virology, 1, 261 (1955).

  2. 2

    Fulton, R. W., Phytopath., 40, 219 (1950).

  3. 3

    Siegel, A., Virology, 8, 470 (1959). Wu, J. H., and Rappaport, I., Virology, 14, 259 (1961). Rappaport, I., and Wu, J. H., Virology, 17, 411 (1962). Wu, J. H., Hudson, W., and Wildman, S. G., Phytopath., 52, 1264 (1962).

  4. 4

    Wu, J. H., and Hudson, W., Virology (in the press).

  5. 5

    Lindner, R. C., Kirkpatrick, H. C., and Weeks, T. E., Phytopath., 49, 78 (1959).

  6. 6

    Rochow, W. F., Phytopath., 46, 133 (1956).

  7. 7

    Brcak, J., Ulrychova, M., and Cech, M., Virology, 16, 105 (1962).

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  1. Department of Botany and Plant Biochemistry, University of California, Los Angeles, 24

    • JIA-HSI WU
    •  & S. G. WILDMAN


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