Abstract
IT is well known that histamine stimulates gastric acid secretion and there is some evidence to suggest that gastric ammonia production may be stimulated concom-itantly1. It seemed possible, therefore, that subjects with an impairment of ammonia clearance might show changes in the blood ammonia level after histamine. The opportunity was taken to measure arterial ammonia levels in subjects with liver disease receiving histamine with an antihistamine as part of a maximal histamine test of gastric function2.
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References
Fitzgerald, O., and Murphy, P., Nature, 162, 896 (1948).
Kay, A. W., Brit. Med. J., ii, 77 (1953).
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TURNER, M., ARPAD, O. Effect of Histamine on Arterial Blood Ammonia in Man. Nature 198, 590–591 (1963). https://doi.org/10.1038/198590a0
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DOI: https://doi.org/10.1038/198590a0
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