Abstract
IN 1957 Smithies1, using the technique of starch-gel electrophoresis, described inherited variants of human β-globulins. Smithies and Hiller2 established the identity of these β-globulins with the iron-binding protein, trans-ferrin, and this was afterwards confirmed with iron-59 and autoradiography3. During the past few years widespread sampling of human populations has demonstrated the existence so far of 14 transferrins. In order of decreasing mobility in starch-gel electrophoresis these are4: B0, BO–1 B1, B1–2, B2, B3, C, D0, D4 (D0–1), Dmontreal Dchi, D1, D2, D3. The present communication reports another transferrin of the B series.
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References
Smithies, O., Nature, 180, 1482 (1957); 181, 1203 (1958).
Smithies, O., and Hiller, O., Biochem. J., 72, 121 (1959).
Giblett, E. R., Hickman, C. G., and Smithies, O., Nature, 183, 1589 (1959).
Parker, W. C., and Bearn, A. G., Science, 137, 854 (1962).
Lai, L. Y. C., Austral. J. Sci., 23, 228 (1961).
Barnicot, N. A., and Kariks, J., Med. J. Austral., 2, 859 (1960). Bennett, J. H., Auricht, C. O., Gray, A. J., Kirk, R. L., and Lai, L. Y. C., Nature, 189, 68 (1961).
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LAI, L. A New Transferrin in New Guinea. Nature 198, 589 (1963). https://doi.org/10.1038/198589a0
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DOI: https://doi.org/10.1038/198589a0
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