Abstract
TUMOUR transplantation in animals by injection of tumour fragments or tissue mince does not offer a quantitative method of implanting a known number of viable cells. Cell suspension techniques give the quantitative data but do not afford a uniform growth in a single implantation site. Often the injected fluid suspension spreads in the tissue and yields more than one tumour or a ‘spread-out’ tumour, the size of which is not a reflexion of cell count only.
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GOTTFRIED, B., PADNOS, M. & MOLOMUT, N. Quantitative Technique for Uniform Tumour Implantation by Trocar in Gel-foam. Nature 197, 1309 (1963). https://doi.org/10.1038/1971309a0
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DOI: https://doi.org/10.1038/1971309a0
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