Abstract
EARLIER work1,2 has indicated a disturbance in iron metabolism in avian erythroblastosis, a virus disease of chickens in which there is an erythroblastic hyperplasia of the bone marrow with the entry of primitive red cells into the circulating blood. In normal birds injected intravenously with iron-59, the radioistope disappears from the plasma and reappears in 24–48 h. In birds with erythroblastosis the activity reappears more quickly1, autoradiographic investigations in blood smears suggesting that most of the activity is associated with the primitive cells2.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Darcel, C. le Q., and Bather, R., Canad. J. Comp. Med., 24, 199 (1960).
Bather, R., Niilo, L., and Darcel, C. le Q., Canad. J. Comp. Med., 24, 326 (1960).
Darcel, C. le Q., Canad. J. Comp. Med., 25, 129 (1961).
Hawk, P. B., Oser, B. L., and Summerson, W. H., Practical Physiological Chemistry (Blakiston, Philadelphia 1947).
Natelson, S., Microtechniques of Clinical Chemistry for the Routine Laboratory (Thomas, Springfield, Illinois, 1957).
Bruckman, G., and Zondek, S. G., Biochem. J., 33, 1845 (1939).
Granick, S., J. Biol. Chem., 146, 451 (1942).
Darcel, C. le Q., Canad. J. Comp. Med., 25, 19 (1961).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
DARCEL, C., DZIUBALO, S. & BATHER, R. Iron Metabolism in Avian Erythroblastosis. Nature 197, 1299–1300 (1963). https://doi.org/10.1038/1971299b0
Issue Date:
DOI: https://doi.org/10.1038/1971299b0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.