Synthesis of Hæm in Normal and Leukæmic Leucocytes

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RECENT investigations suggest that the formation of hæm from iron and protoporphyrin is enzymatic in avian erythrocytes1–4, rat liver5,6 and canine muscle7. The hæmoproteins, such as catalase, peroxidase and the cytochromes, exist in leucocytes8; however, the origin of hæm for these proteins is not apparent. The present study concerns the formation of hæm in a leucocyte system.

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