Abstract
PREVIOUS work has shown that stress by brief immersion in ice-water induces characteristic changes in the number of circulating leucocytes in the male killifish, Fundulus heteroclitus: at 20° C, an initial fall (leucopenia) 1 h after stress is succeeded at 2 h by an increase above the normal level (leucocytosis)1,2. Single injections of ACTH3 produced leucopenia at low doses (0.15 I.U./g), and leucocytosis at higher doses2. Single injections of cortisol (5 µg/g), while causing leucopenia in regressed males and females, produced leucocytosis after 2 h in both breeding and hypophysectomized fish of either sex1.
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References
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BALL, J., SLICHER, A. Influence of Hypophysectomy and of an Adrenocortical Inhibitor (SU-4885) on the Stress-Response of the White Blood Cells in the Teleost Fish, Mollienesia latipinna Le Sueur. Nature 196, 1331–1332 (1962). https://doi.org/10.1038/1961331a0
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DOI: https://doi.org/10.1038/1961331a0
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