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Effect of Cortisone on the Urinary Excretion of Histamine in the Hyperthyroid Rat

Nature volume 196, pages 1213–1214 (1962)Cite this article

Abstract

RECENT work has emphasized that histamine metabolism in the rat may be influenced by adrenocortical1,2 and thyroid3,4 hormones. Various observations also indicate that these two groups of hormones may be functionally related in certain respects. It was therefore of interest to examine the action of cortisone on the urinary excretion of histamine in the hyperthyroid rat. It has been shown3 that the rat treated with thyroxine has a high urinary histamine-level, and there is evidence that the high urinary histamine is the result of an increased rate of histamine synthesis4.

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References

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  2. Angervall, L., Bjurö, T., and Westling, H., Acta Endocrinol., 36, 467 (1961).

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Authors and Affiliations

  1. Department of Clinical Physiology, University of Göteborg, Sweden

    T. BJURÖ, H. WESTLING & H. WETTERQVIST

Authors
  1. T. BJURÖ
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  2. H. WESTLING
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  3. H. WETTERQVIST
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BJURÖ, T., WESTLING, H. & WETTERQVIST, H. Effect of Cortisone on the Urinary Excretion of Histamine in the Hyperthyroid Rat. Nature 196, 1213–1214 (1962). https://doi.org/10.1038/1961213b0

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