Abstract
DR. B. J. RIGBY and co-workers1,2 in their studies on mechanical properties of rat tail tendon have extrapolated a possible explanation for the pathological alterations that occur in rheumatic diseases of humans. They consider the damaging effects of rheumatic diseases to be caused in part by a denaturation of collagen which was a function of temperature. It is our contention that the extrapolation cannot be made for several reasons.
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References
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Bowes, J. H., Elliott, R. G., and Moss, J. A., Nature and Structure of Collagen, edit. by Randall, J. T., 204 (Academic Press, New York, 1953).
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KLEIN, L., CURTISS, P. Rat Tail Tendon Denaturation and Rheumatic Diseases. Nature 194, 305–306 (1962). https://doi.org/10.1038/194305a0
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DOI: https://doi.org/10.1038/194305a0
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