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Oxidation of Anthranilic Acid by a Species of Achromobacter isolated from Soil

Nature volume 194, pages 1099–1100 (1962)Cite this article

Abstract

STUDIES of the microbial decomposition of anthranilic acid have been confined mostly to work with various strains of Pseudomonas spp.1–3 which oxidize anthranilic acid to catechol by an unknown pathway. The role of salicylic acid in this conversion is not clear since reported experiments based on the technique of simultaneous adaptation have yielded divergent results1,4. Sakamoto et al.4 have further shown that cell suspensions, adapted to oxidize anthranilic acid, are inactive towards 3-hydroxyanthranilic acid and 5-hydroxyanthranilic acid. By contrast, the two last-named compounds have been clearly implicated in the breakdown of anthranilic acid by mammalian tissue since both have been isolated from the urine of animals injected with anthranilic acid or o-aminobenzamide5–9.

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References

  1. Suda, M., Hayaishi, O., and Oda, Y., J. Biochem., Japan, 37, 355 (1950).

    Article  CAS  Google Scholar 

  2. Hayaishi, O., and Stanier, R. Y., J. Bact., 62, 691 (1951).

    CAS  PubMed  Google Scholar 

  3. Stanier, R. Y., and Hayaishi, O., J. Bact., 62, 367 (1951).

    CAS  PubMed  Google Scholar 

  4. Sakamoto, Y., Uchida, M., and Ichihara, K., Med. J. Osaka Univ., 3, 477 (1953).

    CAS  Google Scholar 

  5. Bray, H. G., Lake, H. F., Neale, F. C., Thorpe, W. V., and Wood, P. B., Biochem. J., 42, 434 (1948).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Shirai, Y., J. Japan. Biochem. Soc., 22, 223 (1950).

    CAS  Google Scholar 

  7. Shirai, Y., and Uno, S., J. Japan. Biochem. Soc., 23, 51 (1951).

    CAS  Google Scholar 

  8. Kotake, Y., Shibata, Y., and Toratani, A., Proc. Japan. Acad., 32, 774 (1956).

    Article  CAS  Google Scholar 

  9. Hagihara, F., and Okazaki, Y., J. Pharm. Soc., Japan, 76, 362 (1956).

    Article  CAS  Google Scholar 

  10. Ladd, J. N., Austral. J. Biol. Sci. (in the press).

  11. Ke, Y., Gee, L. L., and Durham, N. N., J. Bact., 77, 593 (1959).

    CAS  PubMed  Google Scholar 

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  1. Division of Soils, C.S.I.R.O., Adelaide

    J. N. LADD

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  1. J. N. LADD
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LADD, J. Oxidation of Anthranilic Acid by a Species of Achromobacter isolated from Soil. Nature 194, 1099–1100 (1962). https://doi.org/10.1038/1941099b0

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