Letter | Published:

Rapid Method for Determination of Decarboxylation of Compounds labelled with Carbon-14

Nature volume 193, pages 684685 (17 February 1962) | Download Citation

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Abstract

A RAPID and accurate method of determining the rate of decarboxylation activity of tissues in different types is presented. This method is based on the evolution of 14CO2 from substrate on filter papers impregnated with potassium hydroxide. Filter papers having radioactive compounds has been measured directly by liquid scintillation counting1–3.

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References

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    , and , Biochem. Biophys. Res. Comm., 1, 203 (1959).

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    , and , Biochem. Biophys. Res. Comm., 3, 72 (1960).

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    , and , Science, 131, 1608 (1960).

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    Operational Manual. Packard Tri-Carb Liquid Scintillation Spectrometer (Packard Instrument Co., Inc.).

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    , , and , J. Biol. Chem., 232, 107 (1958).

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Affiliations

  1. University of Tennessee–Atomic Energy Commission, Agricultural Research Laboratory, Oak Ridge, Tennessee.

    • J. CHIRIBOGA
    •  & D. N. ROY

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DOI

https://doi.org/10.1038/193684a0

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