Letter | Published:

Concentration and Partial Purification of Poliovirus by means of Zinc Hydroxide and Ion-exchanging Resin

Nature volume 193, pages 600601 (10 February 1962) | Download Citation

Subjects

Abstract

Newton and Bevis1 concentrated some animal viruses by adding zinc hydroxide to the virus suspension and afterwards dissolving the gel in saturated ethylenediamine tetraacetic acid solution in order to recover the virus. Attempts made in our laboratory to concentrate poliovirus by this method yielded unsatisfactory results.

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References

  1. 1.

    , and , Virology, 8, 344 (1959).

  2. 2.

    , , and , Proc. Soc. Exp. Biol. and Med., 103, 872 (1960).

  3. 3.

    , Brit. J. Exp. Pathol., 40, 452 (1959).

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Author information

Affiliations

  1. Department of Poliomyelitis, Dr. I. Cantacuzino Institute, Bucarest.

    • FLORIAN HORODNICEANU
    • , DINA SERGIESCU
    • , RICHARD KLEIN
    •  & ANDREI AUBERT-COMBIESCU

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DOI

https://doi.org/10.1038/193600b0

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