Letter | Published:

Linkage between Glucose-6-Phosphate Dehydrogenase Deficiency and Colour-Blindness

Nature volume 193, page 506 (03 February 1962) | Download Citation

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Abstract

A LINKAGE investigation has been carried out in American Negroes to confirm that deficiency in glucose-6-phosphate dehydrogenase is sex linked rather than sex limited1, and, if sex linked, to determine the recombination fraction (χ) between the loci for deficiency in glucose-6-phosphate dehydrogenase and colour-blindness; further, through the use of linkage, to see if the difference between the expression of deficiency in glucose-6-phosphate dehydrogenase in Negroes and Caucasians2 is explicable on the basis of different genetic loci in the different ethnic groups.

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Affiliations

  1. Johns Hopkins Hospital, Baltimore, 5, Maryland.

    • I. H. PORTER
    • , J. SCHULZE
    •  & V. A. McKUSICK

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https://doi.org/10.1038/193506a0

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