Abstract
PAPILLOMAS of rabbit skin induced by the virus of Shope are known to undergo complete regression in some animals and to persist indefinitely in others. Carcinomatous change is seen in a high proportion at 6–18 months1. The regression process presents two features of broad significance in the field of tumour immunology: (1) It constitutes rejection of an autologous tumour; (2) The rejection mechanism is effective in some animals and inadequate or absent in others.
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References
Syverton, J. T., Dascomb, H. E., Koomen, jun., J., Wells, E. B., and Berry, G. P., Cancer Res., 10, 379 (1950).
Kidd, J. G., J. Exp. Med., 67, 551 (1938).
Dulbecco, R., and Vogt, M., J. Exp. Med., 99, 167 (1954).
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EVANS, C., GORMAN, L., ITO, Y. et al. A Vaccination Procedure which increases the Frequency of Regressions of Shope Papillomas of Rabbits. Nature 193, 288–289 (1962). https://doi.org/10.1038/193288a0
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DOI: https://doi.org/10.1038/193288a0
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