Letter | Published:

Formation of Histamine and Histamine-like Substances from Histidine by Quartz Dust

Nature volume 192, pages 872873 (02 December 1961) | Download Citation

Subjects

Abstract

IT has been shown1 that quartz dust is capable of participating in a number of oxidative and hydroxylative reactions. The present communication reports the production of histamine, from the interaction of quartz dust with histidine, and the chromatographic isolation of additional products of this reaction, namely, imidazole–carboxylic acids from the lungs of guinea pigs treated with quartz dust.

Access optionsAccess options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

References

  1. 1.

    , and , Nature, 188, 1193 (1960).

  2. 2.

    et al. (U.S.S.R.), quoted in Deutsch. Med. Wochsch., No. 17, 671 (1957).

  3. 3.

    , and , Arch. Exp. Path. and Pharmakol., 186, 269 (1937). , Naturwiss., 25, 589 (1937).

  4. 4.

    , Biochemistry of the Amino Acids, 328–333 (Acad. Press, Inc., New York, 1957).

  5. 5.

    , et al., Biochim. Biophys. Acta, 15, (1954)

Download references

Author information

Affiliations

  1. Pneumoconiosis Research Unit of the South African Council for Scientific and Industrial Research, c/o South African Institute for Medical Research, P.O. Box 1038, Johannesburg.

    • L. W. MARASAS

Authors

  1. Search for L. W. MARASAS in:

About this article

Publication history

Published

DOI

https://doi.org/10.1038/192872a0

Further reading

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.