Letter | Published:

Polysaccharide Content of the Prolapsed Nucleus Pulposus of the Human Intervertebral Disk

Nature volume 192, page 868 (02 December 1961) | Download Citation

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Abstract

THE nucleus pulposus of normal human intervertebral disk contains the two acidic mucopolysaccharides, chondroitin sulphate and keratosulphate1–3. During ageing an increase of collagen occurs4 leading to a decreased ratio of mucopolysaccharide to collagen, although the absolute amount of mucopolysaccharide remains constant4.

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References

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    , and , Acta Chem. Scand., 8, 362 (1954).

  2. 2.

    , , and , Nature, 180, 1341 (1957).

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    , Acta Chem. Scand., 12, 1869 (1958).

  4. 4.

    , , , and , Acta Orthopæd. Scand., 22, 175 (1952).

  5. 5.

    , J. Bone and Joint Surg., 40B, 132 (1958).

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Author information

Affiliations

  1. Bradford Institute of Technology and Royal Infirmary, Bradford.

    • F. HAPPEY
    • , A. WISEMAN
    •  & A. NAYLOR

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DOI

https://doi.org/10.1038/192868a0

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